ABSTRACT
<p><b>OBJECTIVE</b>To investigate the chemical constituents of Hemistepta lyrata.</p><p><b>METHOD</b>The constituents of the EtOAc-soluble portions of the 95% ethanol extract were isolated and purified by means of chromatography. Compounds were identified by their physical characteristics and spectral features.</p><p><b>RESULT</b>Five compounds were isolated and identified as caffeic acid (1), tracheloside (2), uracil (3), 8-carboxymethyl-p-hydroxycinnamic acid (4), and 3-O-p-coumaroylquinic acid (5).</p><p><b>CONCLUSION</b>Compounds 1-5 were isolated from this genus for the first time.</p>
Subject(s)
4-Butyrolactone , Chemistry , Asteraceae , Chemistry , Caffeic Acids , Chemistry , Glucosides , Chemistry , Plants, Medicinal , Chemistry , Uracil , ChemistryABSTRACT
<p><b>AIM</b>To study the chemical constituents of Cypripedium tibeticum.</p><p><b>METHODS</b>Compounds were isolated by repeated silica gel chromatography and purified on Sephadex LH-20 and structures were determined by spectral analysis.</p><p><b>RESULTS</b>Cypritibetquinones A and B were isolated from the ethyl acetate residue and their structures were determined as 7-hydroxy-2-methoxy-1 4-phenanthraquinone (1) and 7-hydroxy-2, 10-dimethoxy-l1 4-phenanthraquinone (2), respectively, by extensive spectral analyses.</p><p><b>CONCLUSION</b>Cypritibetquinones A and B are two new phenanthraquinones.</p>
Subject(s)
Anthraquinones , Chemistry , Molecular Conformation , Molecular Structure , Orchidaceae , Chemistry , Phenanthrenes , Chemistry , Plants, Medicinal , Chemistry , Rhizome , ChemistryABSTRACT
<p><b>AIM</b>To investigate the chemical constituents of the rhizomes of Beesia calthaefolia native to China in order to obtain a more comprehensive understanding of its effective components.</p><p><b>METHODS</b>Compounds were isolated by column chromatography with silica gel. Their structures were elucidated by spectral analysis and chemical evidence. Compounds identified were subjected to pharmacological evaluation.</p><p><b>RESULTS</b>Two novel compounds were isolated and identified as (20S, 24S)-15 alpha-acetoxy-16 beta, 24; 20, 24-diepoxy-9, 19-cyclolanostane-3 beta, 25-diol-3-O-beta-D-xylopyranoside (I) and (20S, 24R)-15 alpha-acetoxy-9, 19-cyclolanostane-3 beta, 16 beta, 20, 24, 25-pentaol-3-O-beta-D-xylopyranoside (II), named beesioside O and beesioside P.</p><p><b>CONCLUSION</b>Compounds I and II are new compounds. Compounds I exhibited immunosuppressive activity and could inhibit angiogenesis as well as inhibit the proliferation of osteoblast. Compound II displayed remarkable inhibition activity against calcium channel receptor.</p>